aagenaes syndrome
antibody
PDL treatment successful in Phase 2 trial
bizjournals.com via Yahoo! Finance - 21 minutes ago PDL BioPharma Inc. and Biogen Idec Inc. said Monday that a Phase 2 trial of the antibody daclizumab had met its endpoint in relapsing multiple sclerosis patients also being treated with the product interferon beta.
antigen
Scientists view antigen peptide binding
UPI - Mar 12 5:24 AM U.S. scientists have developed a method that allows viewing of peptide binding by antigen-presenting cells when they generate an immune response.
antigen processing
AVANT Immunotherapeutics and Select Vaccines Announce Partnership to Develop Improved Viral Vaccines
[Press Release] Business Wire via Yahoo! Finance - Feb 12 4:30 AM NEEDHAM, Mass.----AVANT Immunotherapeutics, Inc. and Select Vaccines Limited , an Australian biotechnology company, today announced a research and development partnership focused on the use of Select Vaccines' virus-like particles as a platform technology for the development of viral vaccines.
antitoxin
'70s microscope a living legacy
Albany Times Union - Mar 09 2:18 AM Equipment was advanced for its time, and still represents Wadsworth lab's innovation
cancer immunotherapy
Oxxon Therapeutics to Be Acquired By Oxford Biomedica
RedNova - Mar 12 5:15 AM OXFORD, England, March 12 /PRNewswire/ -- Oxxo
cell-mediated immunity
Vanderbilt Investigators Testing Vaccine to Slow Malaria's Global March
Newswise - Mar 12 6:21 AM Infectious diseases researchers are seeking healthy adults to help test a vaccine for malaria. While malaria is no longer considered a threat within U.S. borders, according to the World Health Organization (WHO), the disease kills more than 1 million people around the globe each year. Most of its victims are children.
complement system
Potentia Pharmaceuticals Raises $5 Million From Private Investors
RedNova - Mar 07 3:13 PM LOUISVILLE, Ky., March 7 /PRNewswire/ -- Potentia Pharmaceuticals, Inc. announced today that it closed a $5 million round of financing. The funds will be used in part to support the pre-clinical and clinical development of Potentia's main drug candidate, POT-4.
complement system
Potentia Pharmaceuticals Raises $5 Million From Private Investors
RedNova - Mar 07 3:13 PM LOUISVILLE, Ky., March 7 /PRNewswire/ -- Potentia Pharmaceuticals, Inc. announced today that it closed a $5 million round of financing. The funds will be used in part to support the pre-clinical and clinical development of Potentia's main drug candidate, POT-4.
epitope
AlgoNomics Granted Patent Rights for Epibase
[Press Release] Business Wire via Yahoo! Finance - Mar 07 8:38 AM GHENT, Belgium----AlgoNomics NV, the immunoprofiling company, announced today that notice of grant has been received from the European Patent Office for a key patent covering its Epibase® technology.
hapten
AVAX Receives Designation As a Small/Medium Enterprise By the European Medicines Agency
RedNova - Mar 07 5:14 AM AVAX Technologies, Inc. (OTCMarket:AVXT.OB) today announced that the Company, through its wholly owned subsidiary, Genopoeitic SAS, has received notification from the European Medicines Agency (EMEA) that it has been granted designation as a Small/Medium Enterprise (SME).
histamine
Dealing With Springtime Allergies
CBS News - 2 hours, 0 minute ago Springtime is when plants, flowers and trees come alive after a long, cold winter. Unfortunately for many people, it is also when allergies come alive. The Early Show medical contributor Dr. Emily Senay tells how to deal with them.
human leukocyte antigen
QIAGEN Company Receives Innovation & Leadership Of The Year Award
BioresearchOnline - Feb 27 7:52 AM QIAGEN, a provider of sample and assay technologies for research in life sciences, applied testing and molecular diagnostics, announced that its wholly owned subsidiary, Genaco Biomedical Products, Inc., and Luminex Corporation received the 2006 Technology Innovation and Leadership Award from Frost and Sullivan
humoral immunity
Antibody Signal May Redirect Inflammation To Fuel Cancer
Science Daily - Feb 19 11:20 PM As evidence mounts that the body's normally protective inflammation response can drive some precancerous tissues to become fully malignant, UCSF scientists report discovering an apparent trigger to this potentially deadly process.
hypermutation
Primary Immunodeficiency: Complex Genetic Disorders?
RedNova - Feb 17 1:11 AM By Schejbel, Lone; Garred, Peter Classical primary immunodeficiencies (PIDs) are usually monogenic (Mendclian) disorders affecting host defenses. More than 200 clinical phenotypes of PID have been described, and about 100 of them now have a well-defined molecular genetic basis (1).
immune system
Immune System Cells Linked To Heart Failure
Medical News Today - Nov 16 6:08 AM The immune system and, more specifically, cells recruited from it are key players in the muscle dysfunction that results in some forms of heart failure, said Baylor College of Medicine researchers in a report that appears online in the Proceedings of the National Academy of Sciences.Dr. [click link for full article]
immune system
Immune System Cells Linked To Heart Failure
Medical News Today - Nov 16 6:08 AM The immune system and, more specifically, cells recruited from it are key players in the muscle dysfunction that results in some forms of heart failure, said Baylor College of Medicine researchers in a report that appears online in the Proceedings of the National Academy of Sciences.Dr. [click link for full article]
immunosuppression
Stem cells act through multiple mechanisms to benefit mice with neurodegenerative disease
EurekAlert! - Mar 11 11:03 AM (La Jolla, CA, March 11, 2007) Human embryonic stem cells (hESCs) hold great promise for benefiting degenerative diseases, and do so by invoking multiple mechanisms.
immunosuppressive drug
Isotechnika receives USAN approval for generic name for lead immunosuppressive drug
[Press Release] CNW Group via Yahoo! Finance - Mar 12 6:00 AM Isotechnika Inc. announced today that the Company has received approval from United States Adopted Name for naming of its lead immunosuppressive drug, ISA247.
lymphatic system
105-year-old's birthday gifts promote joy
Akron Beacon Journal - Mar 12 1:24 AM Mary Jane Haag's family subscribes to the long-held notion of sending flowers while the recipient can still enjoy them. So each year Mrs. Haag receives roses that correspond to each year of living. They come individually wrapped and delivered, compliments of her son John Haag of Cuyahoga Falls.
major histocompatibility complex
Scientists view antigen peptide binding
UPI - Mar 12 5:24 AM U.S. scientists have developed a method that allows viewing of peptide binding by antigen-presenting cells when they generate an immune response.
monoclonal antibody
BioSystems International Announces Appointment of a New CEO
[Press Release] Business Wire via Yahoo! Finance - Mar 12 7:16 AM EVRY, France----BioSystems International is a French biotechnology company with research laboratories in France and Hungary . BSI's business is focused on the discovery and diagnostic development of biomarkers, based on its proprietary high throughput monoclonal antibody technology.
opsonin
Primary Immunodeficiency: Complex Genetic Disorders?
RedNova - Feb 17 1:11 AM By Schejbel, Lone; Garred, Peter Classical primary immunodeficiencies (PIDs) are usually monogenic (Mendclian) disorders affecting host defenses. More than 200 clinical phenotypes of PID have been described, and about 100 of them now have a well-defined molecular genetic basis (1).
polyclonal antibody
Symphogen and Biovitrum Initiate Phase 1 Clinical Trial with The First Recombinant Polyclonal Antibody to Enter ...
[Press Release] Business Wire via Yahoo! Finance - Mar 12 12:11 AM COPENHAGEN, Denmark & STOCKHOLM, Sweden----Symphogen and Biovitrum today announced the initiation of a Phase 1 clinical trial to test the safety, pharmacokinetics and pharmacodynamics of Sym001 in healthy volunteers.
reticuloendothelial system
New Radiopharmaceuticals for Imaging Rheumatoid Arthritis
RedNova - Feb 17 1:11 AM By Chianelli, M; D'Alessandria, C; Conti, F; Priori, R; Et al Rheumatoid arthritis (RA) is an incapacitating chronic inflammatory disease of the joints that, because of frequent relapses, requires life-long treatment.
toll-like receptor
Anadys Pharmaceuticals to Present at the Cowen & Company's 27th Annual Healthcare Conference
RedNova - Mar 06 5:26 PM SAN DIEGO, March 6 /PRNewswire-FirstCall/ -- Anadys Pharmaceuticals, Inc. announced today that it will present at Cowen & Company's 27th Annual Health Care Conference on Wednesday, March 14, 2007 at 10:15 a.m. ET (7:15 a.m. PT).
Anatomy:
Veins
Arteries
Digestive System
Endocrine System
Immune System
Lower Limb Anatomy
Upper Limb Anatomy
Muscular System
Skeletal System
Nervous System
Central Nervous System
Integumentary System
Reproductive System
Cardiovascular System
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aagenaes syndrome
Aagenaes syndrome
Classification & external resources
| DiseasesDB |
32129 |
A syndrome characterised by congenital hypoplasia of lymph vessels, which causes lymphedema of the legs and recurrent cholestasis in infancy, and slow progress to hepatic cirrhosis and giant-cell hepatitis with fibrosis of the portal tracts1.
The genetic cause is unknown, but it is autosomal recessively inherited and the gene is located to chromosome 15q1,2. A common feature of the condition is a generalised lymphatic anomaly, which may be indicative of the defect being lymphangiogenetic in origin1. The condition is particularly frequent in southern Norway, where more than half the cases are reported from, but is found in patients in other parts of Europe and the U.S.2. It is named after Oystein Aagenaes, a Norwegian paediatrician.
Also called cholestasis-lymphedema syndrome (CLS).
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